. . . . . . . . . . . . . . . . . . "TextLocation" . "Results" . "tscript(p(MGI:Mef2d)) => r(MGI:Ppargc1a)" . "Approximately 2000 hand curated statements drawn from 57 PubMeds." . "Copyright (c) 2011-2012, Selventa. All Rights Reserved." . "BEL Framework Small Corpus Document" . "Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License" . . "1.6" . "We next examined whether mutations of this MEF2 site affects MEF2 activity on the\nPGC-1α promoter. The mutated 2-kb promoter (called ΔMEF2; see Fig. 3A) is no longer\nable to mediate MEF2C or MEF2D induction alone, when activated by CnA or coactivated\nby PGC-1α, suggesting that this site is responsible for the MEF2 action\n(Fig. 3B). Moreover, electrophoretic mobility-shift assays revealed binding of\nMEF2C to this MEF-binding site but not the mutated ΔMEF site in the PGC-1α promoter\n(Fig. 3C). The identity of the MEF2C–DNA complex was confirmed by using an\nanti-MEF2 antibody that leads to a supershift of the DNA–protein complex." . . "support@belframework.org" . "Selventa" . . . . "2014-07-03T14:29:34.383+02:00"^^ . . .