. . . . . . . . . . . . . . . . . . . . "TextLocation" . "Results" . "gtp(p(PFH:\"DNM Family\")) -> tloc(p(HGNC:EGFR),MESHCL:\"Cell Membrane\",MESHCL:Cytoplasm)" . "Approximately 2000 hand curated statements drawn from 57 PubMeds." . "Copyright (c) 2011-2012, Selventa. All Rights Reserved." . "BEL Framework Small Corpus Document" . "Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License" . . "1.6" . "To confirm that EGFR internalization was critical for potentiating EGFR signaling,\na GFP-tagged dominant negative dynamin (dn-dynamin) K44A expression construct\nwas transiently transfected into A549 cells, and the impact of its expression on\nEGF-stimulated signaling was determined (Fig. 7A). The expression of dn-dynamin\n(Fig. 7B) resulted in a ~2-fold decrease in ERK1/2 activation in response to EGF\nstimulation (Fig. 7, A and C); this observation supports the conclusion that internalization\nof EGFR is critical for proper signaling in A549 cells." . . "support@belframework.org" . "Selventa" . . . . "2014-07-03T14:29:33.005+02:00"^^ . . .