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All Rights Reserved. http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Small Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/dc/terms/license Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAFEuFtqKeld3_U9cMI77e2KoucCXLt2HS5nwJGvfe1eM#_7 http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/pav/version 1.6 http://www.tkuhn.ch/bel2nanopub/RAFEuFtqKeld3_U9cMI77e2KoucCXLt2HS5nwJGvfe1eM#_6 http://www.w3.org/ns/prov#value As shown in Fig. 3,d–e, incubation with the PKC inhibitor BIM I (as well as with the β1-neutralizing mAb) blocked dose-dependent VEGF-induced cell adhesion to fibronectin. This involvement of PKC in MM cell adhesion to fibronectin was further confirmed by a dose-dependent increment of adhesion triggered by PMA stimulation (Fig. 3d) similar to that induced by VEGF. Taken together, our results show that VEGF transiently enhances MM cell adhesion to fibronectin, dependent on both PKC and β1 integrin activity. http://www.tkuhn.ch/bel2nanopub/RAFEuFtqKeld3_U9cMI77e2KoucCXLt2HS5nwJGvfe1eM#_6 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/11751905 http://www.tkuhn.ch/bel2nanopub/RAFEuFtqKeld3_U9cMI77e2KoucCXLt2HS5nwJGvfe1eM#_7 http://www.w3.org/2000/01/rdf-schema#comment support@belframework.org http://www.tkuhn.ch/bel2nanopub/RAFEuFtqKeld3_U9cMI77e2KoucCXLt2HS5nwJGvfe1eM#_7 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAFEuFtqKeld3_U9cMI77e2KoucCXLt2HS5nwJGvfe1eM#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/11751905 http://www.tkuhn.ch/bel2nanopub/RAFEuFtqKeld3_U9cMI77e2KoucCXLt2HS5nwJGvfe1eM#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAFEuFtqKeld3_U9cMI77e2KoucCXLt2HS5nwJGvfe1eM#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAFEuFtqKeld3_U9cMI77e2KoucCXLt2HS5nwJGvfe1eM#_6 http://www.tkuhn.ch/bel2nanopub/RAFEuFtqKeld3_U9cMI77e2KoucCXLt2HS5nwJGvfe1eM#pubinfo http://www.tkuhn.ch/bel2nanopub/RAFEuFtqKeld3_U9cMI77e2KoucCXLt2HS5nwJGvfe1eM http://purl.org/dc/terms/created 2014-07-03T14:29:31.214+02:00 http://www.tkuhn.ch/bel2nanopub/RAFEuFtqKeld3_U9cMI77e2KoucCXLt2HS5nwJGvfe1eM http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAFEuFtqKeld3_U9cMI77e2KoucCXLt2HS5nwJGvfe1eM http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234