. . . . . . . . . . . . . . . . . . . . "TextLocation" . "Results" . "tloc(p(HGNC:HDAC4),MESHCL:Cytoplasm,MESHCL:\"Cell Nucleus\") => p(HGNC:HDAC4,pmod(S,K,559))" . "Approximately 2000 hand curated statements drawn from 57 PubMeds." . "Copyright (c) 2011-2012, Selventa. All Rights Reserved." . "BEL Framework Small Corpus Document" . "Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License" . . "1.6" . "As expected, expression of a construct (HDAC4-ΔNLS) lacking these residues rendered\nthe protein entirely cytoplasmic, albeit without impairing the protein's ability\nto aggregate (Figure 6B). Western blot analysis of cells expressing HDAC4- ΔNLS\ndemonstrated this protein to be unable to undergo SUMO-1 modification (Figure\n6C, lane 3), even upon co-expression of exogenous His-SUMO-1 (Figure 6C, lane\n4). This inability, however, is not an intrinsic property of this protein since\nmodification by SUMO-1 occurs as efficiently as for the full-length HDAC4 protein\nusing the in vitro assay (Figure 6C, compare lane 8 with lane 6)." . . "support@belframework.org" . "Selventa" . . . . "2014-07-03T14:29:34.308+02:00"^^ . . .