@prefix this: <http://www.tkuhn.ch/bel2nanopub/RAJM8-Q4atk09_K91vhQrMLuesX1y2sCyPHhceDnOzoww> .
@prefix sub: <http://www.tkuhn.ch/bel2nanopub/RAJM8-Q4atk09_K91vhQrMLuesX1y2sCyPHhceDnOzoww#> .
@prefix beldoc: <http://resource.belframework.org/belframework/20131211/knowledge/small_corpus.bel> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix dce: <http://purl.org/dc/elements/1.1/> .
@prefix pav: <http://purl.org/pav/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix belv: <http://www.selventa.com/vocabulary/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix go: <http://amigo.geneontology.org/amigo/term/GO:> .
@prefix Protein: <http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080> .
@prefix mgi: <http://www.informatics.jax.org/marker/MGI:> .
@prefix geneProductOf: <http://purl.obolibrary.org/obo/RO_0002204> .
@prefix hasAgent: <http://semanticscience.org/resource/SIO_000139> .
@prefix RNA: <http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_33697> .
@prefix mesh: <http://purl.bioontology.org/ontology/MSH/> .
@prefix occursIn: <http://purl.obolibrary.org/obo/BFO_0000066> .
@prefix hasAnnotation: <http://semanticscience.org/resource/SIO_000255> .
@prefix species: <http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=> .
@prefix obo: <http://purl.obolibrary.org/obo/> .
@prefix pubmed: <http://www.ncbi.nlm.nih.gov/pubmed/> .
@prefix orcid: <http://orcid.org/> .

sub:Head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubinfo;
    a np:Nanopublication .
}

sub:assertion {
  sub:_1 hasAgent: sub:_2;
    a go:0042789 .
  
  sub:_2 geneProductOf: mgi:88494;
    a Protein: .
  
  sub:_3 geneProductOf: mgi:1342774;
    a RNA: .
  
  sub:_4 occursIn: mesh:D018482, obo:UBERON_0002107, species:10090;
    hasAnnotation: sub:_5;
    rdf:object sub:_3;
    rdf:predicate belv:increases;
    rdf:subject sub:_1;
    a rdf:Statement .
  
  sub:_5 dct:subject "TextLocation";
    rdf:value "Results" .
  
  sub:assertion rdfs:label "tscript(p(MGI:Creb1)) -> r(MGI:Ppargc1a)" .
}

sub:provenance {
  beldoc: dce:description "Approximately 2000 hand curated statements drawn from 57 PubMeds.";
    dce:rights "Copyright (c) 2011-2012, Selventa. All Rights Reserved.";
    dce:title "BEL Framework Small Corpus Document";
    dct:license "Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License";
    pav:authoredBy sub:_7;
    pav:version "20131211" .
  
  sub:_6 prov:value """CaMKIV has been shown to phosphorylate and activate many proteins, including CREB.
Because CREB has been shown to be an important activator of PGC-1α gene expression
in the fasted liver (24), we used the dominant-negative ACREB protein to examine
a potential role for CREB in the CaMKIV-mediated control of the PGC-1α promoter.
Although ACREB alone had no effect on the PGC-1α promoter, this protein severely
reduced the activation of the PGC-1α promoter by CaMKIV alone or CaMKIV
in combination with CnA (Fig. 1A).""";
    prov:wasQuotedFrom pubmed:12764228 .
  
  sub:_7 rdfs:comment "support@belframework.org";
    rdfs:label "Selventa" .
  
  sub:assertion prov:hadPrimarySource pubmed:12764228;
    prov:wasDerivedFrom beldoc:, sub:_6 .
}

sub:pubinfo {
  this: dct:created "2014-07-03T14:31:18.143+02:00"^^xsd:dateTime;
    pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 .
}