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All Rights Reserved. http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Small Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/dc/terms/license Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RALsDJ60Mr3DOXO6tBqORAuWmSbsYvovdmcAx5nI2B3VE#_5 http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/pav/version 1.6 http://www.tkuhn.ch/bel2nanopub/RALsDJ60Mr3DOXO6tBqORAuWmSbsYvovdmcAx5nI2B3VE#_4 http://www.w3.org/ns/prov#value Here, we show that Wnt/β-catenin signaling regulates proximal-distal differentiation of airway epithelium. Inhibition of Wnt/β-catenin signaling, either by expression of Dkk1 or by tissue-specific deletion of β-catenin, results in disruption of distal airway development and expansion of proximal airways. http://www.tkuhn.ch/bel2nanopub/RALsDJ60Mr3DOXO6tBqORAuWmSbsYvovdmcAx5nI2B3VE#_4 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/15907834 http://www.tkuhn.ch/bel2nanopub/RALsDJ60Mr3DOXO6tBqORAuWmSbsYvovdmcAx5nI2B3VE#_5 http://www.w3.org/2000/01/rdf-schema#comment support@belframework.org http://www.tkuhn.ch/bel2nanopub/RALsDJ60Mr3DOXO6tBqORAuWmSbsYvovdmcAx5nI2B3VE#_5 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RALsDJ60Mr3DOXO6tBqORAuWmSbsYvovdmcAx5nI2B3VE#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/15907834 http://www.tkuhn.ch/bel2nanopub/RALsDJ60Mr3DOXO6tBqORAuWmSbsYvovdmcAx5nI2B3VE#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://www.tkuhn.ch/bel2nanopub/RALsDJ60Mr3DOXO6tBqORAuWmSbsYvovdmcAx5nI2B3VE#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RALsDJ60Mr3DOXO6tBqORAuWmSbsYvovdmcAx5nI2B3VE#_4 http://www.tkuhn.ch/bel2nanopub/RALsDJ60Mr3DOXO6tBqORAuWmSbsYvovdmcAx5nI2B3VE#pubinfo http://www.tkuhn.ch/bel2nanopub/RALsDJ60Mr3DOXO6tBqORAuWmSbsYvovdmcAx5nI2B3VE http://purl.org/dc/terms/created 2014-07-03T14:29:31.991+02:00 http://www.tkuhn.ch/bel2nanopub/RALsDJ60Mr3DOXO6tBqORAuWmSbsYvovdmcAx5nI2B3VE http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RALsDJ60Mr3DOXO6tBqORAuWmSbsYvovdmcAx5nI2B3VE http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234