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Results
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p(HGNC:SELE) -> bp(GOBP:"heterotypic cell-cell adhesion")
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Approximately 2000 hand curated statements drawn from 57 PubMeds.
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Copyright (c) 2011-2012, Selventa. All Rights Reserved.
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BEL Framework Small Corpus Document
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Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License
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As illustrated in Fig.2, A–C, the expression of E-selectin correlated with an increased
adhesion of both colon carcinoma HT-29 cells and HL-60 leukemia cells to
a monolayer of HUVEC. After 30 min, the number of HT-29 cells that adhered to HUVEC-expressing
E-selectin, following activation with TNFα, was 5-fold higher than
when adhering to inactivated HUVEC. Similarly, HT-29 cells quickly adhered to
immobilized recombinant human E-selectin/Fc chimera (data not shown). An anti-E-selectin
neutralizing antibody, but not a matched isotype antibody, decreased the
adhesion of both cancer cell types to the activated endothelium (Fig. 2, A–C).
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support@belframework.org
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Selventa
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2014-07-03T14:31:17.689+02:00
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