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a(SCHEM:"serum insulin") -| p(MGI:Acaca,pmod(P))
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Approximately 61,000 statements.
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the cellular concentration of malonyl-CoA is directly related to the activity of acetyl-CoA carboxylase the short-term regulation of acetyl-CoA carboxylase involves the phosphorylation and dephosphorylation of the enzyme in the fasting animal, a high [glucagon]/[insulin] ratio causes the phosphorylation and inactivation of acetyl-CoA carboxylase as a consequence, the concentration of malonyl-CoA and the rate of fatty acid synthesis decrease, while the rate of beta-oxidation increases a decrease of the [glucagon]/[insulin] ratio reverses these effects thus, both fatty acid synthesis and fatty acid oxidation are regulated by the ratio of [glucagon]/[insulin]
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2014-07-03T14:29:43.186+02:00
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