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All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAO9iu4-6lJ0eCdjCwBYtZlyQ2SZ2QAqsGLziA70N43Mo#_8 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RAO9iu4-6lJ0eCdjCwBYtZlyQ2SZ2QAqsGLziA70N43Mo#_6 http://purl.org/dc/elements/1.1/identifier Mol Sys Biol 2005 May msb4100014 http://www.tkuhn.ch/bel2nanopub/RAO9iu4-6lJ0eCdjCwBYtZlyQ2SZ2QAqsGLziA70N43Mo#_6 http://purl.org/dc/elements/1.1/title Mol Sys Biol 2005 May msb4100014 http://www.tkuhn.ch/bel2nanopub/RAO9iu4-6lJ0eCdjCwBYtZlyQ2SZ2QAqsGLziA70N43Mo#_6 http://purl.org/dc/elements/1.1/type Other http://www.tkuhn.ch/bel2nanopub/RAO9iu4-6lJ0eCdjCwBYtZlyQ2SZ2QAqsGLziA70N43Mo#_7 http://www.w3.org/ns/prov#value The epidermal growth factor receptor (EGFR) signaling pathway is one of the most important pathways that regulate growth, survival, proliferation, and differentiation in mammalian cells. Reflecting this importance, it is one of the best-investigated signaling systems, both experimentally and computationally, and several computational models have been developed for dynamic analysis. A map of molecular interactions of the EGFR signaling system is a valuable resource for research in this area. In this paper, we present a comprehensive pathway map of EGFR signaling and other related pathways. The map reveals that the overall architecture of the pathway is a bow-tie (or hourglass) structure with several feedback loops. The map is created using CellDesigner software that enables us to graphically represent interactions using a welldefined and consistent graphical notation, and to store it in Systems Biology Markup Language (SBML). http://www.tkuhn.ch/bel2nanopub/RAO9iu4-6lJ0eCdjCwBYtZlyQ2SZ2QAqsGLziA70N43Mo#_7 http://www.w3.org/ns/prov#wasQuotedFrom http://www.tkuhn.ch/bel2nanopub/RAO9iu4-6lJ0eCdjCwBYtZlyQ2SZ2QAqsGLziA70N43Mo#_6 http://www.tkuhn.ch/bel2nanopub/RAO9iu4-6lJ0eCdjCwBYtZlyQ2SZ2QAqsGLziA70N43Mo#_8 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAO9iu4-6lJ0eCdjCwBYtZlyQ2SZ2QAqsGLziA70N43Mo#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.tkuhn.ch/bel2nanopub/RAO9iu4-6lJ0eCdjCwBYtZlyQ2SZ2QAqsGLziA70N43Mo#_6 http://www.tkuhn.ch/bel2nanopub/RAO9iu4-6lJ0eCdjCwBYtZlyQ2SZ2QAqsGLziA70N43Mo#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAO9iu4-6lJ0eCdjCwBYtZlyQ2SZ2QAqsGLziA70N43Mo#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAO9iu4-6lJ0eCdjCwBYtZlyQ2SZ2QAqsGLziA70N43Mo#_7 http://www.tkuhn.ch/bel2nanopub/RAO9iu4-6lJ0eCdjCwBYtZlyQ2SZ2QAqsGLziA70N43Mo#pubinfo http://www.tkuhn.ch/bel2nanopub/RAO9iu4-6lJ0eCdjCwBYtZlyQ2SZ2QAqsGLziA70N43Mo http://purl.org/dc/terms/created 2014-07-03T14:29:44.391+02:00 http://www.tkuhn.ch/bel2nanopub/RAO9iu4-6lJ0eCdjCwBYtZlyQ2SZ2QAqsGLziA70N43Mo http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAO9iu4-6lJ0eCdjCwBYtZlyQ2SZ2QAqsGLziA70N43Mo http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234