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TextLocation
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Review
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kin(p(HGNC:IRAK4)) => kin(p(HGNC:IRAK1))
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http://purl.org/dc/elements/1.1/description
Approximately 2000 hand curated statements drawn from 57 PubMeds.
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Copyright (c) 2011-2012, Selventa. All Rights Reserved.
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BEL Framework Small Corpus Document
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Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License
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1.6
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support@belframework.org
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Selventa
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MyD88 also binds to IRAK-4 and thereby facilitates IRAK-4 phosphorylation of critical
residue(s) in the kinase activation loop of IRAK-1, triggering IRAK-1's own
kinase activity. Once activated, IRAK-1 likely autophosphorylates residues in its
N terminus. TRAF6 is also recruited to the receptor complex via interaction with
IRAK-1.
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2014-07-03T14:29:33.158+02:00
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