. . . . . . . . . . . . . . . . . "TextLocation" . "Review" . "bp(GOBP:\"integrin-mediated signaling pathway\") -> bp(GOBP:\"extracellular matrix assembly\")" . "p(HGNC:VHL) -> (bp(GOBP:\"integrin-mediated signaling pathway\") -> bp(GOBP:\"extracellular matrix assembly\"))" . "Approximately 2000 hand curated statements drawn from 57 PubMeds." . "Copyright (c) 2011-2012, Selventa. All Rights Reserved." . "BEL Framework Small Corpus Document" . "Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License" . . "20131211" . "Nevertheless, the restored ability of pVHL-positive transfectants to assemble extracellular\nfibronectin was mediated by b1 integrins, implying that pVHL controls\nECM assembly, at least in part, through integrin signalling [46]. A recent development\nhas demonstrated that an ubiquitin-like molecule, NEDD8, covalently modifies\npVHL and that a neddylation- defective pVHL mutant, despite retaining its ability\nto degrade HIF, fails to promote the assembly of a fibronectin matrix [47]." . . "support@belframework.org" . "Selventa" . . . . "2014-07-03T14:31:15.433+02:00"^^ . . .