sub:provenance {
beldoc: dce:description "Approximately 61,000 statements." ;
dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
dce:title "BEL Framework Large Corpus Document" ;
pav:authoredBy sub:_6 ;
pav:version "1.4" .
sub:_4 dce:identifier "Weizmann Institute open day 2002: cancer research and therapy" ;
dce:title "Weizmann Institute open day 2002: cancer research and therapy" ;
dce:type "Other" .
sub:_5 prov:value "Other novel E2F-regulated genes, identified using the DNA microarray analysis, are involved in mitosis and DNA repair. The identification of mitotic genes, including the kinases Bub1b and cdc2, as E2F-regulated genes indicates that E2F affects cell cycle progression both at the S-phase and during mitosis. The molecular mechanism(s) of E2F-dependent regulation of mitotic genes is currently being studied. The identification of DNA repair genes, including MSH2, MSH6 and BRCA1, as E2F-regulated genes raises the possibility that E2F plays a role in the response to DNA damage. This notion is supported by recent reports demonstrating that various DNA damaging agents induce an increase in E2F-1 protein level." ;
prov:wasQuotedFrom sub:_4 .
sub:_6 rdfs:label "Selventa" .
sub:assertion prov:hadPrimarySource sub:_4 ;
prov:wasDerivedFrom beldoc: ,
sub:_5 .
}