. . . . . . . . . . . . . "p(PFH:\"E2F Family\") -> r(HGNC:MSH6)" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "1.4" . "Weizmann Institute open day 2002: cancer research and therapy" . "Weizmann Institute open day 2002: cancer research and therapy" . "Other" . "Other novel E2F-regulated genes, identified using the DNA microarray analysis, are involved in mitosis and DNA repair. The identification of mitotic genes, including the kinases Bub1b and cdc2, as E2F-regulated genes indicates that E2F affects cell cycle progression both at the S-phase and during mitosis. The molecular mechanism(s) of E2F-dependent regulation of mitotic genes is currently being studied. The identification of DNA repair genes, including MSH2, MSH6 and BRCA1, as E2F-regulated genes raises the possibility that E2F plays a role in the response to DNA damage. This notion is supported by recent reports demonstrating that various DNA damaging agents induce an increase in E2F-1 protein level." . . "Selventa" . . . . "2014-07-03T14:29:44.235+02:00"^^ . . .