@prefix this: . @prefix sub: . @prefix beldoc: . @prefix rdfs: . @prefix rdf: . @prefix xsd: . @prefix dct: . @prefix dce: . @prefix pav: . @prefix np: . @prefix belv: . @prefix prov: . @prefix go: . @prefix Protein: . @prefix hgnc: . @prefix geneProductOf: . @prefix hasAgent: . @prefix chebi: . @prefix hasAnnotation: . @prefix species: . @prefix occursIn: . @prefix mesh: . @prefix atcc: . @prefix pubmed: . @prefix orcid: . sub:Head { this: np:hasAssertion sub:assertion; np:hasProvenance sub:provenance; np:hasPublicationInfo sub:pubinfo; a np:Nanopublication . } sub:assertion { sub:_1 hasAgent: sub:_2; a go:0016301 . sub:_2 geneProductOf: hgnc:3942; a Protein: . sub:_3 geneProductOf: hgnc:6081; a Protein: . sub:_4 rdf:object sub:_3; rdf:predicate belv:increases; rdf:subject chebi:5418; a rdf:Statement . sub:_5 occursIn: mesh:D007515, atcc:CRL-2057.aspx, species:9606; hasAnnotation: sub:_6; rdf:object sub:_4; rdf:predicate belv:increases; rdf:subject sub:_1; a rdf:Statement . sub:_6 dct:subject "TextLocation"; rdf:value "Results" . sub:assertion rdfs:label "a(CHEBI:glucose) -> p(HGNC:INS)", "kin(p(HGNC:MTOR)) -> (a(CHEBI:glucose) -> p(HGNC:INS))" . } sub:provenance { beldoc: dce:description "Approximately 2000 hand curated statements drawn from 57 PubMeds."; dce:rights "Copyright (c) 2011-2012, Selventa. All Rights Reserved."; dce:title "BEL Framework Small Corpus Document"; dct:license "Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License"; pav:authoredBy sub:_8; pav:version "1.6" . sub:_7 prov:value """we combined the stimulation with glucose or insulin with the cotreatment with inhibitors of the insulin receptor tyrosine kinase [hydroxy-2-naphthalenylmethylphosphonic acid trisacetoxymethyl ester (HNMPA)], PI 3-kinase (wortmannin and LY294002), and mTOR (rapamycin). As shown in Figs. 1 and 2, HNMPA, wortmannin, LY294002, and rapamycin inhibited both glucose- and insulin-stimulated insulin biosynthesis in both human pancreatic islets and RIN β-cells."""; prov:wasQuotedFrom pubmed:15001544 . sub:_8 rdfs:comment "support@belframework.org"; rdfs:label "Selventa" . sub:assertion prov:hadPrimarySource pubmed:15001544; prov:wasDerivedFrom beldoc:, sub:_7 . } sub:pubinfo { this: dct:created "2014-07-03T14:29:33.044+02:00"^^xsd:dateTime; pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 . }