@prefix dc: . @prefix this: . @prefix sub: . @prefix beldoc: . @prefix rdfs: . @prefix rdf: . @prefix xsd: . @prefix dce: . @prefix pav: . @prefix np: . @prefix belv: . @prefix prov: . @prefix Protein: . @prefix mgi: . @prefix geneProductOf: . @prefix hasPart: . @prefix schem: . @prefix pfm: . @prefix proteinModification: . @prefix psimod: . @prefix mesh: . @prefix occursIn: . @prefix hasAnnotation: . @prefix species: . @prefix pubmed: . @prefix orcid: . sub:Head { this: np:hasAssertion sub:assertion; np:hasProvenance sub:provenance; np:hasPublicationInfo sub:pubinfo; a np:Nanopublication . } sub:assertion { sub:_1 hasPart: schem:Lipopolysaccharide, sub:_2 . sub:_2 geneProductOf: mgi:107656; a Protein: . sub:_3 belv:variantOf pfm:MAPK%20Erk1%2F3%20Family; a proteinModification:, psimod:00696 . sub:_4 occursIn: mesh:D004727, species:10090; hasAnnotation: sub:_5; rdf:object sub:_3; rdf:predicate belv:increases; rdf:subject sub:_1; a rdf:Statement . sub:_5 dc:subject "TextLocation"; rdf:value "Abstract" . sub:assertion rdfs:label "composite(p(MGI:Ifng),a(SCHEM:Lipopolysaccharide)) -> p(PFM:\"MAPK Erk1/3 Family\",pmod(P))" . } sub:provenance { beldoc: dce:description "Approximately 2000 hand curated statements drawn from 57 PubMeds."; dce:rights "Copyright (c) 2011-2012, Selventa. All Rights Reserved."; dce:title "BEL Framework Small Corpus Document"; dc:license "Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License"; pav:authoredBy sub:_7; pav:version "1.6" . sub:_6 prov:value """Further, LPS + IFNγ -induced expression of iNOS and Nox1 was attenuated by the mitogen-activated protein kinase kinase 1/2 (MEK1/2) inhibitor PD98059, the JNK inhibitor SP600125, the Jak2 inhibitor AG490 and the NFκB inhibitor MG132, but not by the p38 mitogen-activated protein kinase inhibitor SB203580. LPS + IFNγ stimulated phosphorylation of ERK, JNK and Jak2, and degradation of IκB, but only Jak2 phosphorylation was sensitive to tripterine (50-200 nM). Further, tripterine diminished the increased vascular permeability in inflamed air pouches."""; prov:wasQuotedFrom pubmed:19508391 . sub:_7 rdfs:comment "support@belframework.org"; rdfs:label "Selventa" . sub:assertion prov:hadPrimarySource pubmed:19508391; prov:wasDerivedFrom beldoc:, sub:_6 . } sub:pubinfo { this: dc:created "2014-07-03T14:29:31.404+02:00"^^xsd:dateTime; pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 . }