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TextLocation
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Abstract
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p(HGNC:ITGB1) -> bp(GOBP:"cell migration")
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p(HGNC:VEGFA) -> (p(HGNC:ITGB1) -> bp(GOBP:"cell migration"))
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Approximately 2000 hand curated statements drawn from 57 PubMeds.
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Copyright (c) 2011-2012, Selventa. All Rights Reserved.
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BEL Framework Small Corpus Document
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Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License
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We show that protein kinase C (PKC) alpha is translocated to the plasma membrane and
activated by adhesion of MM cells to fibronectin and VEGF. We identify beta(1)
integrin modulating VEGF-triggered MM cell migration on fibronectin. We show
that transient enhancement of MM cell adhesion to fibronectin triggered by VEGF
is dependent on the activity of both PKC and beta(1) integrin. Moreover, we demonstrate
that PKC alpha is constitutively associated with beta(1) integrin.
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support@belframework.org
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Selventa
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2014-07-03T14:31:16.111+02:00
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