http://www.tkuhn.ch/bel2nanopub/RAV3gTrtxKqrmElQdWNSmE6xdTMdN0s2BjNNKVwdQu4rg#Head http://www.tkuhn.ch/bel2nanopub/RAV3gTrtxKqrmElQdWNSmE6xdTMdN0s2BjNNKVwdQu4rg http://www.nanopub.org/nschema#hasAssertion http://www.tkuhn.ch/bel2nanopub/RAV3gTrtxKqrmElQdWNSmE6xdTMdN0s2BjNNKVwdQu4rg#assertion http://www.tkuhn.ch/bel2nanopub/RAV3gTrtxKqrmElQdWNSmE6xdTMdN0s2BjNNKVwdQu4rg http://www.nanopub.org/nschema#hasProvenance http://www.tkuhn.ch/bel2nanopub/RAV3gTrtxKqrmElQdWNSmE6xdTMdN0s2BjNNKVwdQu4rg#provenance http://www.tkuhn.ch/bel2nanopub/RAV3gTrtxKqrmElQdWNSmE6xdTMdN0s2BjNNKVwdQu4rg http://www.nanopub.org/nschema#hasPublicationInfo http://www.tkuhn.ch/bel2nanopub/RAV3gTrtxKqrmElQdWNSmE6xdTMdN0s2BjNNKVwdQu4rg#pubinfo http://www.tkuhn.ch/bel2nanopub/RAV3gTrtxKqrmElQdWNSmE6xdTMdN0s2BjNNKVwdQu4rg http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://www.tkuhn.ch/bel2nanopub/RAV3gTrtxKqrmElQdWNSmE6xdTMdN0s2BjNNKVwdQu4rg#assertion http://www.tkuhn.ch/bel2nanopub/RAV3gTrtxKqrmElQdWNSmE6xdTMdN0s2BjNNKVwdQu4rg#_1 http://semanticscience.org/resource/SIO_000139 http://www.tkuhn.ch/bel2nanopub/RAV3gTrtxKqrmElQdWNSmE6xdTMdN0s2BjNNKVwdQu4rg#_2 http://www.tkuhn.ch/bel2nanopub/RAV3gTrtxKqrmElQdWNSmE6xdTMdN0s2BjNNKVwdQu4rg#_1 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://amigo.geneontology.org/amigo/term/GO:0005525 http://www.tkuhn.ch/bel2nanopub/RAV3gTrtxKqrmElQdWNSmE6xdTMdN0s2BjNNKVwdQu4rg#_2 http://purl.obolibrary.org/obo/RO_0002204 http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=9855 http://www.tkuhn.ch/bel2nanopub/RAV3gTrtxKqrmElQdWNSmE6xdTMdN0s2BjNNKVwdQu4rg#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RAV3gTrtxKqrmElQdWNSmE6xdTMdN0s2BjNNKVwdQu4rg#_3 http://semanticscience.org/resource/SIO_000139 http://www.tkuhn.ch/bel2nanopub/RAV3gTrtxKqrmElQdWNSmE6xdTMdN0s2BjNNKVwdQu4rg#_4 http://www.tkuhn.ch/bel2nanopub/RAV3gTrtxKqrmElQdWNSmE6xdTMdN0s2BjNNKVwdQu4rg#_3 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://amigo.geneontology.org/amigo/term/GO:0016301 http://www.tkuhn.ch/bel2nanopub/RAV3gTrtxKqrmElQdWNSmE6xdTMdN0s2BjNNKVwdQu4rg#_4 http://purl.obolibrary.org/obo/RO_0002204 http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=1097 http://www.tkuhn.ch/bel2nanopub/RAV3gTrtxKqrmElQdWNSmE6xdTMdN0s2BjNNKVwdQu4rg#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RAV3gTrtxKqrmElQdWNSmE6xdTMdN0s2BjNNKVwdQu4rg#_5 http://purl.obolibrary.org/obo/BFO_0000066 http://purl.bioontology.org/ontology/MSH/D003593 http://www.tkuhn.ch/bel2nanopub/RAV3gTrtxKqrmElQdWNSmE6xdTMdN0s2BjNNKVwdQu4rg#_5 http://purl.obolibrary.org/obo/BFO_0000066 http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606 http://www.tkuhn.ch/bel2nanopub/RAV3gTrtxKqrmElQdWNSmE6xdTMdN0s2BjNNKVwdQu4rg#_5 http://semanticscience.org/resource/SIO_000255 http://www.tkuhn.ch/bel2nanopub/RAV3gTrtxKqrmElQdWNSmE6xdTMdN0s2BjNNKVwdQu4rg#_6 http://www.tkuhn.ch/bel2nanopub/RAV3gTrtxKqrmElQdWNSmE6xdTMdN0s2BjNNKVwdQu4rg#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#object http://www.tkuhn.ch/bel2nanopub/RAV3gTrtxKqrmElQdWNSmE6xdTMdN0s2BjNNKVwdQu4rg#_3 http://www.tkuhn.ch/bel2nanopub/RAV3gTrtxKqrmElQdWNSmE6xdTMdN0s2BjNNKVwdQu4rg#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate http://www.selventa.com/vocabulary/directlyIncreases http://www.tkuhn.ch/bel2nanopub/RAV3gTrtxKqrmElQdWNSmE6xdTMdN0s2BjNNKVwdQu4rg#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#subject http://www.tkuhn.ch/bel2nanopub/RAV3gTrtxKqrmElQdWNSmE6xdTMdN0s2BjNNKVwdQu4rg#_1 http://www.tkuhn.ch/bel2nanopub/RAV3gTrtxKqrmElQdWNSmE6xdTMdN0s2BjNNKVwdQu4rg#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement http://www.tkuhn.ch/bel2nanopub/RAV3gTrtxKqrmElQdWNSmE6xdTMdN0s2BjNNKVwdQu4rg#_6 http://purl.org/dc/terms/subject TextLocation http://www.tkuhn.ch/bel2nanopub/RAV3gTrtxKqrmElQdWNSmE6xdTMdN0s2BjNNKVwdQu4rg#_6 http://www.w3.org/1999/02/22-rdf-syntax-ns#value Review http://www.tkuhn.ch/bel2nanopub/RAV3gTrtxKqrmElQdWNSmE6xdTMdN0s2BjNNKVwdQu4rg#assertion http://www.w3.org/2000/01/rdf-schema#label gtp(p(HGNC:RAP1A)) => kin(p(HGNC:BRAF)) http://www.tkuhn.ch/bel2nanopub/RAV3gTrtxKqrmElQdWNSmE6xdTMdN0s2BjNNKVwdQu4rg#provenance http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/dc/elements/1.1/description Approximately 2000 hand curated statements drawn from 57 PubMeds. http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/dc/elements/1.1/rights Copyright (c) 2011-2012, Selventa. All Rights Reserved. http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Small Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/dc/terms/license Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAV3gTrtxKqrmElQdWNSmE6xdTMdN0s2BjNNKVwdQu4rg#_8 http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/pav/version 1.6 http://www.tkuhn.ch/bel2nanopub/RAV3gTrtxKqrmElQdWNSmE6xdTMdN0s2BjNNKVwdQu4rg#_7 http://www.w3.org/ns/prov#value Both B-Raf and C-Raf can bind to other small GTPases, most notably Rap1.115,131,132 The effector domains of Rap1 and Ras are nearly identical, but activation of these proteins produces vastly different downstream effects. Furthermore, Rap1 mediates distinct effects after binding to various Raf isoforms. The B-Raf–Rap1 complex activates B-Raf, whereas the C-Raf–Rap1 interaction does not activate C-Raf and, in fact, may be inhibitory.115,132,133 This occurs because Rap1 binds to the CRD of C-Raf with higher affinity than Ras and excludes Ras from binding. http://www.tkuhn.ch/bel2nanopub/RAV3gTrtxKqrmElQdWNSmE6xdTMdN0s2BjNNKVwdQu4rg#_7 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/16170185 http://www.tkuhn.ch/bel2nanopub/RAV3gTrtxKqrmElQdWNSmE6xdTMdN0s2BjNNKVwdQu4rg#_8 http://www.w3.org/2000/01/rdf-schema#comment support@belframework.org http://www.tkuhn.ch/bel2nanopub/RAV3gTrtxKqrmElQdWNSmE6xdTMdN0s2BjNNKVwdQu4rg#_8 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAV3gTrtxKqrmElQdWNSmE6xdTMdN0s2BjNNKVwdQu4rg#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/16170185 http://www.tkuhn.ch/bel2nanopub/RAV3gTrtxKqrmElQdWNSmE6xdTMdN0s2BjNNKVwdQu4rg#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAV3gTrtxKqrmElQdWNSmE6xdTMdN0s2BjNNKVwdQu4rg#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAV3gTrtxKqrmElQdWNSmE6xdTMdN0s2BjNNKVwdQu4rg#_7 http://www.tkuhn.ch/bel2nanopub/RAV3gTrtxKqrmElQdWNSmE6xdTMdN0s2BjNNKVwdQu4rg#pubinfo http://www.tkuhn.ch/bel2nanopub/RAV3gTrtxKqrmElQdWNSmE6xdTMdN0s2BjNNKVwdQu4rg http://purl.org/dc/terms/created 2014-07-03T14:29:30.490+02:00 http://www.tkuhn.ch/bel2nanopub/RAV3gTrtxKqrmElQdWNSmE6xdTMdN0s2BjNNKVwdQu4rg http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAV3gTrtxKqrmElQdWNSmE6xdTMdN0s2BjNNKVwdQu4rg http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234