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All Rights Reserved. http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Small Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/dc/terms/license Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAV4u-bQc7ctzNcxRt4wNNdo9AMcQOBuaeuDfi5CGciyg#_6 http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/pav/version 1.6 http://www.tkuhn.ch/bel2nanopub/RAV4u-bQc7ctzNcxRt4wNNdo9AMcQOBuaeuDfi5CGciyg#_5 http://www.w3.org/ns/prov#value It has been shown recently that ubiquitination plays an important role in TAK1 activation (26, 27). IKK activation by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex composed of Ubc13 and Uev1A as well as the TAK1·kinase complex. TRAF6 can interact through its RING finger domain with Ubc13 in the Ubc13·Uev1A complex. 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