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All Rights Reserved. http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Small Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/dc/terms/license Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAX0b2a9RNuD8_Yefa83OjCj-i6hPjah4CKXPKzi6vR2U#_6 http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/pav/version 1.6 http://www.tkuhn.ch/bel2nanopub/RAX0b2a9RNuD8_Yefa83OjCj-i6hPjah4CKXPKzi6vR2U#_5 http://www.w3.org/ns/prov#value In ECs, VEGF stimulates ARF6 association with Rac1, which is cotemporaneous with Rac1 activation. The dominant negative ARF6 (T27N),inhibits VEGF-stimulated GTP-loading of Rac1, ROS production, and VEGFR2 autophosphorylation. These results suggest that ARF6 is an upstream mediator for Rac1, which may contribute to ROS production that mediates VEGFR2 autophosphorylation in ECs (Fig. 1). http://www.tkuhn.ch/bel2nanopub/RAX0b2a9RNuD8_Yefa83OjCj-i6hPjah4CKXPKzi6vR2U#_5 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/17511588 http://www.tkuhn.ch/bel2nanopub/RAX0b2a9RNuD8_Yefa83OjCj-i6hPjah4CKXPKzi6vR2U#_6 http://www.w3.org/2000/01/rdf-schema#comment support@belframework.org http://www.tkuhn.ch/bel2nanopub/RAX0b2a9RNuD8_Yefa83OjCj-i6hPjah4CKXPKzi6vR2U#_6 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAX0b2a9RNuD8_Yefa83OjCj-i6hPjah4CKXPKzi6vR2U#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/17511588 http://www.tkuhn.ch/bel2nanopub/RAX0b2a9RNuD8_Yefa83OjCj-i6hPjah4CKXPKzi6vR2U#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAX0b2a9RNuD8_Yefa83OjCj-i6hPjah4CKXPKzi6vR2U#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAX0b2a9RNuD8_Yefa83OjCj-i6hPjah4CKXPKzi6vR2U#_5 http://www.tkuhn.ch/bel2nanopub/RAX0b2a9RNuD8_Yefa83OjCj-i6hPjah4CKXPKzi6vR2U#pubinfo http://www.tkuhn.ch/bel2nanopub/RAX0b2a9RNuD8_Yefa83OjCj-i6hPjah4CKXPKzi6vR2U http://purl.org/dc/terms/created 2014-07-03T14:29:33.924+02:00 http://www.tkuhn.ch/bel2nanopub/RAX0b2a9RNuD8_Yefa83OjCj-i6hPjah4CKXPKzi6vR2U http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAX0b2a9RNuD8_Yefa83OjCj-i6hPjah4CKXPKzi6vR2U http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234