. . . . . . . . . . . . . . . "TextLocation" . "Review" . "p(HGNC:IL6) -> bp(GO:\"macrophage differentiation\")" . "Approximately 2000 hand curated statements drawn from 57 PubMeds." . "Copyright (c) 2011-2012, Selventa. All Rights Reserved." . "BEL Framework Small Corpus Document" . "Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License" . . "1.6" . "It is known that IL-6 induces growth arrest and macrophage differentiation in the\nmurine myeloid leukemic cell line M1. The essential role of STAT3 in the IL-6-induced\nmacrophage differentiation of M1 cells was demonstrated by using dominant\nnegative forms of STAT3 [67], which inhibit both IL-6-induced growth arrest and\nmacrophage differentiation in M1 transformants. Blocking STAT3 activation inhibits\nIL-6-induced repression of c-Myb and c-Myc, but not EGR-1 induction [68], while\nIL-6 enhances the growth of M1 cells when STAT3 is suppressed." . . "support@belframework.org" . "Selventa" . . . . "2014-07-03T14:29:33.540+02:00"^^ . . .