. . . . . . . . . . . . . . . . . . . . . "TextLocation" . "Review" . "p(PFH:\"IL1 Family\") -> complex(p(HGNC:MYD88),p(HGNC:IRAK1))" . "Approximately 2000 hand curated statements drawn from 57 PubMeds." . "Copyright (c) 2011-2012, Selventa. All Rights Reserved." . "BEL Framework Small Corpus Document" . "Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License" . . "1.6" . "Although the kinase activity of IRAK-1 increases strongly following IL-1 stimulation,\nIRAK-1 kinase activity is not required for its signaling function, because\noverexpression of a kinase-defective mutant of IRAK-1 is observed to strongly induce\nNF-κB activation in cells otherwise deficient for IRAK-1. Upon stimulation,\nIRAK-1 is recruited to the receptor through a homophilic interaction with the DD\nof MyD88." . . "support@belframework.org" . "Selventa" . . . . "2014-07-03T14:29:33.156+02:00"^^ . . .