. . . . . . . . . . . . . . . . . "TextLocation" . "Legend" . "p(HGNC:VHL) -| tscript(p(HGNC:HIF1A))" . "Approximately 2000 hand curated statements drawn from 57 PubMeds." . "Copyright (c) 2011-2012, Selventa. All Rights Reserved." . "BEL Framework Small Corpus Document" . "Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License" . . "1.6" . "Figure 4. The role of hypoxia-inducible factor (HIF) in conferring tumour growth potential.\nIn solid tumours, HIFa is stabilised under conditions of low oxygen due\nto a lack of vascularisation and the subsequent evolution of a hypoxic microenvironment.\nIn a VHL-null tumour, HIFa is constitutively active, and can initiate\ngenetic programmes within the entire population of cells that would normally be\nactivated only under hypoxic conditions." . . "support@belframework.org" . "Selventa" . . . . "2014-07-03T14:29:30.360+02:00"^^ . . .