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Review
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bp(GO:"response to hypoxia") -> r(HGNC:FLT1)
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Approximately 2000 hand curated statements drawn from 57 PubMeds.
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Copyright (c) 2011-2012, Selventa. All Rights Reserved.
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BEL Framework Small Corpus Document
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Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License
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In hypoxia, VEGF transcription is upregulated by HIF18, 19, mRNA stability is increased
by binding of proteins to specific sequences in the 3' UTR71, and an internal
ribosomal entry site allows preserved translation in the face of normal cellular
hypoxic shutdown72. The biological activity of secreted VEGF is further influenced
by hypoxia-inducible expression of the Flt-1 receptor49,
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support@belframework.org
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Selventa
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2014-07-03T14:29:32.284+02:00
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