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All Rights Reserved. http://resource.belframework.org/belframework/20131211/knowledge/small_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Small Corpus Document http://resource.belframework.org/belframework/20131211/knowledge/small_corpus.bel http://purl.org/dc/terms/license Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License http://resource.belframework.org/belframework/20131211/knowledge/small_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAc897lI_aAXc_Mn3azHBNCkbwWMj1gieCmf_iwzp1Mhw#_6 http://resource.belframework.org/belframework/20131211/knowledge/small_corpus.bel http://purl.org/pav/version 20131211 http://www.tkuhn.ch/bel2nanopub/RAc897lI_aAXc_Mn3azHBNCkbwWMj1gieCmf_iwzp1Mhw#_5 http://www.w3.org/ns/prov#value Apoptosis is executed through the activation of caspases. To further verify the effect of tobacco smoke in the induction of apoptosis, the levels of cleaved caspases 8, 9, and 3 in rat lungs were determined. In agreement with the apoptotic results described above, exposure of rats to 80 mg/m3 tobacco smoke resulted in significantly increased levels of cleaved caspases 8, 9, and 3, indicating the activation of these caspases (Fig. 7B). 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