. . . . . . . . . . . . . . . . . . "TextLocation" . "Results" . "tscript(p(MGI:Ppargc1a)) -> r(MGI:Ppargc1a)" . "Approximately 2000 hand curated statements drawn from 57 PubMeds." . "Copyright (c) 2011-2012, Selventa. All Rights Reserved." . "BEL Framework Small Corpus Document" . "Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License" . . "20131211" . "Real-time PCR primers were designed for the PGC-1α 3' untranslated region that allows\nfor determination of the levels of ectopically expressed and endogenous PGC-1α.\nAs shown in Fig. 4B and as expected, ectopic PGC-1α is detected only in the\nmuscle of transgenic mice. Strikingly, a 7-fold elevation of endogenous PGC-1α\nmRNA was seen in the transgenic animals as compared with wild-type mice (Fig. 4B).\nA robust increase in the transcript levels of cytochrome c and myoglobin also\nwas observed in the RNA isolated from skeletal muscle of the transgenic mice,\nwhereas GAPDH transcript levels remained unchanged (Fig. 4B). These results indicate\na regulation of PGC-1α transcription by PGC-1α protein in an apparent autoregulatory\nloop." . . "support@belframework.org" . "Selventa" . . . . "2014-07-03T14:31:18.174+02:00"^^ . . .