http://www.tkuhn.ch/bel2nanopub/RAeyLSiUnwBDTh9hpAplwx6uAQuQVueMZCnumY5hpf0oU#Head http://www.tkuhn.ch/bel2nanopub/RAeyLSiUnwBDTh9hpAplwx6uAQuQVueMZCnumY5hpf0oU http://www.nanopub.org/nschema#hasAssertion http://www.tkuhn.ch/bel2nanopub/RAeyLSiUnwBDTh9hpAplwx6uAQuQVueMZCnumY5hpf0oU#assertion http://www.tkuhn.ch/bel2nanopub/RAeyLSiUnwBDTh9hpAplwx6uAQuQVueMZCnumY5hpf0oU http://www.nanopub.org/nschema#hasProvenance http://www.tkuhn.ch/bel2nanopub/RAeyLSiUnwBDTh9hpAplwx6uAQuQVueMZCnumY5hpf0oU#provenance http://www.tkuhn.ch/bel2nanopub/RAeyLSiUnwBDTh9hpAplwx6uAQuQVueMZCnumY5hpf0oU http://www.nanopub.org/nschema#hasPublicationInfo http://www.tkuhn.ch/bel2nanopub/RAeyLSiUnwBDTh9hpAplwx6uAQuQVueMZCnumY5hpf0oU#pubinfo http://www.tkuhn.ch/bel2nanopub/RAeyLSiUnwBDTh9hpAplwx6uAQuQVueMZCnumY5hpf0oU http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://www.tkuhn.ch/bel2nanopub/RAeyLSiUnwBDTh9hpAplwx6uAQuQVueMZCnumY5hpf0oU#assertion http://www.tkuhn.ch/bel2nanopub/RAeyLSiUnwBDTh9hpAplwx6uAQuQVueMZCnumY5hpf0oU#_1 http://purl.obolibrary.org/obo/RO_0002204 http://www.informatics.jax.org/marker/MGI:1329040 http://www.tkuhn.ch/bel2nanopub/RAeyLSiUnwBDTh9hpAplwx6uAQuQVueMZCnumY5hpf0oU#_1 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RAeyLSiUnwBDTh9hpAplwx6uAQuQVueMZCnumY5hpf0oU#_2 http://purl.obolibrary.org/obo/RO_0002204 http://www.informatics.jax.org/marker/MGI:88180 http://www.tkuhn.ch/bel2nanopub/RAeyLSiUnwBDTh9hpAplwx6uAQuQVueMZCnumY5hpf0oU#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_33697 http://www.tkuhn.ch/bel2nanopub/RAeyLSiUnwBDTh9hpAplwx6uAQuQVueMZCnumY5hpf0oU#_3 http://purl.obolibrary.org/obo/BFO_0000066 http://purl.bioontology.org/ontology/MSH/D008168 http://www.tkuhn.ch/bel2nanopub/RAeyLSiUnwBDTh9hpAplwx6uAQuQVueMZCnumY5hpf0oU#_3 http://purl.obolibrary.org/obo/BFO_0000066 http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=10090 http://www.tkuhn.ch/bel2nanopub/RAeyLSiUnwBDTh9hpAplwx6uAQuQVueMZCnumY5hpf0oU#_3 http://semanticscience.org/resource/SIO_000255 http://www.tkuhn.ch/bel2nanopub/RAeyLSiUnwBDTh9hpAplwx6uAQuQVueMZCnumY5hpf0oU#_4 http://www.tkuhn.ch/bel2nanopub/RAeyLSiUnwBDTh9hpAplwx6uAQuQVueMZCnumY5hpf0oU#_3 http://www.w3.org/1999/02/22-rdf-syntax-ns#object http://www.tkuhn.ch/bel2nanopub/RAeyLSiUnwBDTh9hpAplwx6uAQuQVueMZCnumY5hpf0oU#_2 http://www.tkuhn.ch/bel2nanopub/RAeyLSiUnwBDTh9hpAplwx6uAQuQVueMZCnumY5hpf0oU#_3 http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate http://www.selventa.com/vocabulary/decreases http://www.tkuhn.ch/bel2nanopub/RAeyLSiUnwBDTh9hpAplwx6uAQuQVueMZCnumY5hpf0oU#_3 http://www.w3.org/1999/02/22-rdf-syntax-ns#subject http://www.tkuhn.ch/bel2nanopub/RAeyLSiUnwBDTh9hpAplwx6uAQuQVueMZCnumY5hpf0oU#_1 http://www.tkuhn.ch/bel2nanopub/RAeyLSiUnwBDTh9hpAplwx6uAQuQVueMZCnumY5hpf0oU#_3 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement http://www.tkuhn.ch/bel2nanopub/RAeyLSiUnwBDTh9hpAplwx6uAQuQVueMZCnumY5hpf0oU#_4 http://purl.org/dc/terms/subject TextLocation http://www.tkuhn.ch/bel2nanopub/RAeyLSiUnwBDTh9hpAplwx6uAQuQVueMZCnumY5hpf0oU#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#value Results http://www.tkuhn.ch/bel2nanopub/RAeyLSiUnwBDTh9hpAplwx6uAQuQVueMZCnumY5hpf0oU#assertion http://www.w3.org/2000/01/rdf-schema#label p(MGI:Dkk1) -| r(MGI:Bmp4) http://www.tkuhn.ch/bel2nanopub/RAeyLSiUnwBDTh9hpAplwx6uAQuQVueMZCnumY5hpf0oU#provenance http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/dc/elements/1.1/description Approximately 2000 hand curated statements drawn from 57 PubMeds. http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/dc/elements/1.1/rights Copyright (c) 2011-2012, Selventa. All Rights Reserved. http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Small Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/dc/terms/license Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAeyLSiUnwBDTh9hpAplwx6uAQuQVueMZCnumY5hpf0oU#_6 http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/pav/version 1.6 http://www.tkuhn.ch/bel2nanopub/RAeyLSiUnwBDTh9hpAplwx6uAQuQVueMZCnumY5hpf0oU#_5 http://www.w3.org/ns/prov#value In SP-C/Dkk1 embryos, however, BMP4 expression is significantly reduced (Fig. 5J). As discussed above, at E12.5, the efficiency of β-catenin excision in many SP-C/rtTA:tetO-cre X β-cateninflox embryos is less than 100% in some embryos resulting in a mosaic pattern of β-catenin expression in the lung airway epithelium. However, this result proves advantageous since we can determine in a precise cell specific manner whether loss of β-catenin leads to a loss of BMP4. As expected, BMP4 and β-catenin are expressed at high levels in distal airway epithelium in wild-type lungs at E12.5 (Figs. 5K– M). Lungs exhibiting mosaic expression of β-catenin also express BMP4 in a mosaic pattern that closely correlates with presence of β-catenin (Figs. 5N–P). Complete loss of β-catenin leads to a complete loss of BMP4 expression (Figs. 5Q–S). http://www.tkuhn.ch/bel2nanopub/RAeyLSiUnwBDTh9hpAplwx6uAQuQVueMZCnumY5hpf0oU#_5 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/15907834 http://www.tkuhn.ch/bel2nanopub/RAeyLSiUnwBDTh9hpAplwx6uAQuQVueMZCnumY5hpf0oU#_6 http://www.w3.org/2000/01/rdf-schema#comment support@belframework.org http://www.tkuhn.ch/bel2nanopub/RAeyLSiUnwBDTh9hpAplwx6uAQuQVueMZCnumY5hpf0oU#_6 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAeyLSiUnwBDTh9hpAplwx6uAQuQVueMZCnumY5hpf0oU#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/15907834 http://www.tkuhn.ch/bel2nanopub/RAeyLSiUnwBDTh9hpAplwx6uAQuQVueMZCnumY5hpf0oU#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAeyLSiUnwBDTh9hpAplwx6uAQuQVueMZCnumY5hpf0oU#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAeyLSiUnwBDTh9hpAplwx6uAQuQVueMZCnumY5hpf0oU#_5 http://www.tkuhn.ch/bel2nanopub/RAeyLSiUnwBDTh9hpAplwx6uAQuQVueMZCnumY5hpf0oU#pubinfo http://www.tkuhn.ch/bel2nanopub/RAeyLSiUnwBDTh9hpAplwx6uAQuQVueMZCnumY5hpf0oU http://purl.org/dc/terms/created 2014-07-03T14:29:32.033+02:00 http://www.tkuhn.ch/bel2nanopub/RAeyLSiUnwBDTh9hpAplwx6uAQuQVueMZCnumY5hpf0oU http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAeyLSiUnwBDTh9hpAplwx6uAQuQVueMZCnumY5hpf0oU http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234