http://www.tkuhn.ch/bel2nanopub/RAldSZrtM62ty-Bx1zFpWOhJf6sLIw_OvJmpBwEHwCkuo#Head http://www.tkuhn.ch/bel2nanopub/RAldSZrtM62ty-Bx1zFpWOhJf6sLIw_OvJmpBwEHwCkuo http://www.nanopub.org/nschema#hasAssertion http://www.tkuhn.ch/bel2nanopub/RAldSZrtM62ty-Bx1zFpWOhJf6sLIw_OvJmpBwEHwCkuo#assertion http://www.tkuhn.ch/bel2nanopub/RAldSZrtM62ty-Bx1zFpWOhJf6sLIw_OvJmpBwEHwCkuo http://www.nanopub.org/nschema#hasProvenance http://www.tkuhn.ch/bel2nanopub/RAldSZrtM62ty-Bx1zFpWOhJf6sLIw_OvJmpBwEHwCkuo#provenance http://www.tkuhn.ch/bel2nanopub/RAldSZrtM62ty-Bx1zFpWOhJf6sLIw_OvJmpBwEHwCkuo http://www.nanopub.org/nschema#hasPublicationInfo http://www.tkuhn.ch/bel2nanopub/RAldSZrtM62ty-Bx1zFpWOhJf6sLIw_OvJmpBwEHwCkuo#pubinfo http://www.tkuhn.ch/bel2nanopub/RAldSZrtM62ty-Bx1zFpWOhJf6sLIw_OvJmpBwEHwCkuo http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://www.tkuhn.ch/bel2nanopub/RAldSZrtM62ty-Bx1zFpWOhJf6sLIw_OvJmpBwEHwCkuo#assertion http://www.tkuhn.ch/bel2nanopub/RAldSZrtM62ty-Bx1zFpWOhJf6sLIw_OvJmpBwEHwCkuo#_1 http://semanticscience.org/resource/SIO_000139 http://www.tkuhn.ch/bel2nanopub/RAldSZrtM62ty-Bx1zFpWOhJf6sLIw_OvJmpBwEHwCkuo#_2 http://www.tkuhn.ch/bel2nanopub/RAldSZrtM62ty-Bx1zFpWOhJf6sLIw_OvJmpBwEHwCkuo#_1 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://amigo.geneontology.org/amigo/term/GO:0005525 http://www.tkuhn.ch/bel2nanopub/RAldSZrtM62ty-Bx1zFpWOhJf6sLIw_OvJmpBwEHwCkuo#_2 http://purl.obolibrary.org/obo/RO_0002204 http://resource.belframework.org/belframework/20131211/namespace/selventa-protein-families/RAS%20Family http://www.tkuhn.ch/bel2nanopub/RAldSZrtM62ty-Bx1zFpWOhJf6sLIw_OvJmpBwEHwCkuo#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RAldSZrtM62ty-Bx1zFpWOhJf6sLIw_OvJmpBwEHwCkuo#_3 http://semanticscience.org/resource/SIO_000139 http://www.tkuhn.ch/bel2nanopub/RAldSZrtM62ty-Bx1zFpWOhJf6sLIw_OvJmpBwEHwCkuo#_4 http://www.tkuhn.ch/bel2nanopub/RAldSZrtM62ty-Bx1zFpWOhJf6sLIw_OvJmpBwEHwCkuo#_3 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://amigo.geneontology.org/amigo/term/GO:0016301 http://www.tkuhn.ch/bel2nanopub/RAldSZrtM62ty-Bx1zFpWOhJf6sLIw_OvJmpBwEHwCkuo#_4 http://purl.obolibrary.org/obo/RO_0002204 http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=6847 http://www.tkuhn.ch/bel2nanopub/RAldSZrtM62ty-Bx1zFpWOhJf6sLIw_OvJmpBwEHwCkuo#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RAldSZrtM62ty-Bx1zFpWOhJf6sLIw_OvJmpBwEHwCkuo#_5 http://purl.obolibrary.org/obo/BFO_0000066 http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606 http://www.tkuhn.ch/bel2nanopub/RAldSZrtM62ty-Bx1zFpWOhJf6sLIw_OvJmpBwEHwCkuo#_5 http://semanticscience.org/resource/SIO_000255 http://www.tkuhn.ch/bel2nanopub/RAldSZrtM62ty-Bx1zFpWOhJf6sLIw_OvJmpBwEHwCkuo#_6 http://www.tkuhn.ch/bel2nanopub/RAldSZrtM62ty-Bx1zFpWOhJf6sLIw_OvJmpBwEHwCkuo#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#object http://www.tkuhn.ch/bel2nanopub/RAldSZrtM62ty-Bx1zFpWOhJf6sLIw_OvJmpBwEHwCkuo#_3 http://www.tkuhn.ch/bel2nanopub/RAldSZrtM62ty-Bx1zFpWOhJf6sLIw_OvJmpBwEHwCkuo#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate http://www.selventa.com/vocabulary/increases http://www.tkuhn.ch/bel2nanopub/RAldSZrtM62ty-Bx1zFpWOhJf6sLIw_OvJmpBwEHwCkuo#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#subject http://www.tkuhn.ch/bel2nanopub/RAldSZrtM62ty-Bx1zFpWOhJf6sLIw_OvJmpBwEHwCkuo#_1 http://www.tkuhn.ch/bel2nanopub/RAldSZrtM62ty-Bx1zFpWOhJf6sLIw_OvJmpBwEHwCkuo#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement http://www.tkuhn.ch/bel2nanopub/RAldSZrtM62ty-Bx1zFpWOhJf6sLIw_OvJmpBwEHwCkuo#_6 http://purl.org/dc/terms/subject TextLocation http://www.tkuhn.ch/bel2nanopub/RAldSZrtM62ty-Bx1zFpWOhJf6sLIw_OvJmpBwEHwCkuo#_6 http://www.w3.org/1999/02/22-rdf-syntax-ns#value Review http://www.tkuhn.ch/bel2nanopub/RAldSZrtM62ty-Bx1zFpWOhJf6sLIw_OvJmpBwEHwCkuo#assertion http://www.w3.org/2000/01/rdf-schema#label gtp(p(SFAM:"RAS Family")) -> kin(p(HGNC:MAP2K7)) http://www.tkuhn.ch/bel2nanopub/RAldSZrtM62ty-Bx1zFpWOhJf6sLIw_OvJmpBwEHwCkuo#provenance http://resource.belframework.org/belframework/20131211/knowledge/small_corpus.bel http://purl.org/dc/elements/1.1/description Approximately 2000 hand curated statements drawn from 57 PubMeds. http://resource.belframework.org/belframework/20131211/knowledge/small_corpus.bel http://purl.org/dc/elements/1.1/rights Copyright (c) 2011-2012, Selventa. All Rights Reserved. http://resource.belframework.org/belframework/20131211/knowledge/small_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Small Corpus Document http://resource.belframework.org/belframework/20131211/knowledge/small_corpus.bel http://purl.org/dc/terms/license Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License http://resource.belframework.org/belframework/20131211/knowledge/small_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAldSZrtM62ty-Bx1zFpWOhJf6sLIw_OvJmpBwEHwCkuo#_8 http://resource.belframework.org/belframework/20131211/knowledge/small_corpus.bel http://purl.org/pav/version 20131211 http://www.tkuhn.ch/bel2nanopub/RAldSZrtM62ty-Bx1zFpWOhJf6sLIw_OvJmpBwEHwCkuo#_7 http://www.w3.org/ns/prov#value Localization of GTP-bound Ras to the inner surface of the cell membrane activates several downstream effectors, most notably the serine/threonine kinase Raf, which is the first signaling element in the MAPK pathway. 2,67,68 As shown in Figure 1, other downstream effectors of Ras include the PI3K cell survival pathway, the small GTP-binding proteins Rac and Rho, and the stress-activated protein kinase pathway (also referred to as the c-jun N-terminal kinase [JNK] pathway). 69-71 In addition, in response to cellular stress and cytokine stimulation mediated through Ras, the dual-specificity p38MAPK kinases (MKK3 and MKK6) and the JNK kinases (MKK4 and MKK7) phosphorylate p38MAPK and JNK, respectively. 72-76 http://www.tkuhn.ch/bel2nanopub/RAldSZrtM62ty-Bx1zFpWOhJf6sLIw_OvJmpBwEHwCkuo#_7 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/16170185 http://www.tkuhn.ch/bel2nanopub/RAldSZrtM62ty-Bx1zFpWOhJf6sLIw_OvJmpBwEHwCkuo#_8 http://www.w3.org/2000/01/rdf-schema#comment support@belframework.org http://www.tkuhn.ch/bel2nanopub/RAldSZrtM62ty-Bx1zFpWOhJf6sLIw_OvJmpBwEHwCkuo#_8 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAldSZrtM62ty-Bx1zFpWOhJf6sLIw_OvJmpBwEHwCkuo#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/16170185 http://www.tkuhn.ch/bel2nanopub/RAldSZrtM62ty-Bx1zFpWOhJf6sLIw_OvJmpBwEHwCkuo#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/20131211/knowledge/small_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAldSZrtM62ty-Bx1zFpWOhJf6sLIw_OvJmpBwEHwCkuo#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAldSZrtM62ty-Bx1zFpWOhJf6sLIw_OvJmpBwEHwCkuo#_7 http://www.tkuhn.ch/bel2nanopub/RAldSZrtM62ty-Bx1zFpWOhJf6sLIw_OvJmpBwEHwCkuo#pubinfo http://www.tkuhn.ch/bel2nanopub/RAldSZrtM62ty-Bx1zFpWOhJf6sLIw_OvJmpBwEHwCkuo http://purl.org/dc/terms/created 2014-07-03T14:31:15.511+02:00 http://www.tkuhn.ch/bel2nanopub/RAldSZrtM62ty-Bx1zFpWOhJf6sLIw_OvJmpBwEHwCkuo http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAldSZrtM62ty-Bx1zFpWOhJf6sLIw_OvJmpBwEHwCkuo http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234