@prefix this: <http://www.tkuhn.ch/bel2nanopub/RArwwoj0KEqBANkr-x1Kc6SOCEb5HWxXaRdsoDKjV1QtU> .
@prefix sub: <http://www.tkuhn.ch/bel2nanopub/RArwwoj0KEqBANkr-x1Kc6SOCEb5HWxXaRdsoDKjV1QtU#> .
@prefix beldoc: <http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix dce: <http://purl.org/dc/elements/1.1/> .
@prefix pav: <http://purl.org/pav/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix belv: <http://www.selventa.com/vocabulary/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix Protein: <http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080> .
@prefix rgd: <http://rgd.mcw.edu/rgdweb/report/gene/main.html?id=> .
@prefix geneProductOf: <http://purl.obolibrary.org/obo/RO_0002204> .
@prefix go: <http://amigo.geneontology.org/amigo/term/GO:> .
@prefix pfr: <http://resource.belframework.org/belframework/1.0/namespace/selventa-named-rat-protein-families/> .
@prefix hasAgent: <http://semanticscience.org/resource/SIO_000139> .
@prefix mesh: <http://purl.bioontology.org/ontology/MSH/> .
@prefix occursIn: <http://purl.obolibrary.org/obo/BFO_0000066> .
@prefix hasAnnotation: <http://semanticscience.org/resource/SIO_000255> .
@prefix species: <http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=> .
@prefix pubmed: <http://www.ncbi.nlm.nih.gov/pubmed/> .
@prefix orcid: <http://orcid.org/> .

sub:Head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubinfo;
    a np:Nanopublication .
}

sub:assertion {
  sub:_1 geneProductOf: rgd:2868;
    a Protein: .
  
  sub:_2 hasAgent: sub:_3;
    a go:0016301 .
  
  sub:_3 geneProductOf: pfr:Rps6kb%20Family;
    a Protein: .
  
  sub:_4 occursIn: mesh:D002460, mesh:D018482, species:10116;
    hasAnnotation: sub:_5;
    rdf:object sub:_2;
    rdf:predicate belv:increases;
    rdf:subject sub:_1;
    a rdf:Statement .
  
  sub:_5 dct:subject "TextLocation";
    rdf:value "Results" .
  
  sub:assertion rdfs:label "p(RGD:Igf1) -> kin(p(PFR:\"Rps6kb Family\"))" .
}

sub:provenance {
  beldoc: dce:description "Approximately 2000 hand curated statements drawn from 57 PubMeds.";
    dce:rights "Copyright (c) 2011-2012, Selventa. All Rights Reserved.";
    dce:title "BEL Framework Small Corpus Document";
    dct:license "Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License";
    pav:authoredBy sub:_7;
    pav:version "1.6" .
  
  sub:_6 prov:value """Intracellular signaling. Infusion of IGF-I resulted in an approximate fivefold increase
in the phosphorylation of ERKs 1 and 2 (Fig. 4), whereas the total ERK levels
were unchanged vs. contralateral muscles (data not shown). Coinfusion (IGF+PD)
completely blunted the increase in ERK1 phosphorylation and significantly reduced
the increase in ERK2 phosphorylation (Fig. 4B). Similar to ERK2, the phosphorylation
of S6K1 was increased fivefold in the IGF and 2.8-fold in the IGF+PD
muscles (Fig. 5). The infusion protocols did not impact the total amount of S6K1
(data not shown).""";
    prov:wasQuotedFrom pubmed:12959952 .
  
  sub:_7 rdfs:comment "support@belframework.org";
    rdfs:label "Selventa" .
  
  sub:assertion prov:hadPrimarySource pubmed:12959952;
    prov:wasDerivedFrom beldoc:, sub:_6 .
}

sub:pubinfo {
  this: dct:created "2014-07-03T14:29:34.214+02:00"^^xsd:dateTime;
    pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 .
}