. . . . . . . . . . . . . . "TextLocation" . "Results" . "complex(p(HGNC:FLT1),p(PFH:\"PIK3R Class IA Family\"))" . "Approximately 2000 hand curated statements drawn from 57 PubMeds." . "Copyright (c) 2011-2012, Selventa. All Rights Reserved." . "BEL Framework Small Corpus Document" . "Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License" . . "1.6" . "We have shown recently that Flt-1 VEGFR is expressed in the human MM cell line and\npatient MM cells and is tyrosine-phosphorylated upon VEGF stimulation (12). Because\nFlt-1 and the p85 subunit of PI 3-kinase were associated when overexpressed\nin yeast cells (54), we next determined whether this interaction is biologically\nsignificant in MM cells. Flt-1 was immunoprecipitated from VEGF treated and non-treated\nMM.1S cells followed by immunoblotting with anti-p85 Ab. As illustrated\nin Fig.5a, p85 is constitutively associated with Flt-1, suggesting that PI 3-kinase\nparticipates in Flt-1-mediated VEGF signal transduction." . . "support@belframework.org" . "Selventa" . . . . "2014-07-03T14:29:31.251+02:00"^^ . . .