. . . . . . . . . . . . . . . . "TextLocation" . "Results" . "a(CHEBIID:50864) -> p(HGNC:AKT1,pmod(P,S,473))" . "Approximately 2000 hand curated statements drawn from 57 PubMeds." . "Copyright (c) 2011-2012, Selventa. All Rights Reserved." . "BEL Framework Small Corpus Document" . "Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License" . . "1.6" . "To determine whether PKA-induced PKB activation accounts for GSK-3 phosphorylation\nafter treatment with 8-Br-cAMP, forskolin, or isoproterenol, PKB phosphorylation\nat serine 473 and threonine 308, which is crucial for activation of PKB (20),\nwas assessed. As expected, insulin and IGF-1 strongly stimulated phosphorylation\nof PKB at serine 473 in NIH 3T3 or Rat1 cells (Fig. 2B). In contrast, 8-Br-cAMP,\nforskolin, and isoproterenol did not significantly alter PKB phosphorylation\nat serine 473 (Fig. 2B). Similar results were obtained with a threonine 308 phosphorylation-specific\nantibody (data not shown)." . . "support@belframework.org" . "Selventa" . . . . "2014-07-03T14:29:34.689+02:00"^^ . . .