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TextLocation
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Abstract
http://www.tkuhn.ch/bel2nanopub/RAtincC7EowNCTJP3cMLK9iAHSXryIAJaEDERYTyqZj0o#assertion
http://www.w3.org/2000/01/rdf-schema#label
complex(p(HGNC:KDR),p(HGNC:ITGAV),p(HGNC:ITGB3))
http://www.tkuhn.ch/bel2nanopub/RAtincC7EowNCTJP3cMLK9iAHSXryIAJaEDERYTyqZj0o#provenance
http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel
http://purl.org/dc/elements/1.1/description
Approximately 2000 hand curated statements drawn from 57 PubMeds.
http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel
http://purl.org/dc/elements/1.1/rights
Copyright (c) 2011-2012, Selventa. All Rights Reserved.
http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel
http://purl.org/dc/elements/1.1/title
BEL Framework Small Corpus Document
http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel
http://purl.org/dc/terms/license
Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License
http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel
http://purl.org/pav/authoredBy
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http://purl.org/pav/version
1.6
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Here we examine the nature of the physical interaction between the αvβ3 integrin and
two receptor tyrosine kinases (RTKs), the platelet-derived growth factor receptor
β (PDGF-Rβ) and the vascular endothelial growth factor receptor 2 (VEGF-R2,
also known as KDR and flk-1). Both of these RTKs associate with the αvβ3 integrin
but do not associate with β1 integrins. Furthermore, growth factor stimulation
of these RTKs promotes increased cell proliferation and migration when cells
are attached to the αvβ3 ligand, vitronectin.
http://www.tkuhn.ch/bel2nanopub/RAtincC7EowNCTJP3cMLK9iAHSXryIAJaEDERYTyqZj0o#_6
http://www.w3.org/ns/prov#wasQuotedFrom
http://www.ncbi.nlm.nih.gov/pubmed/10964931
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http://www.w3.org/2000/01/rdf-schema#comment
support@belframework.org
http://www.tkuhn.ch/bel2nanopub/RAtincC7EowNCTJP3cMLK9iAHSXryIAJaEDERYTyqZj0o#_7
http://www.w3.org/2000/01/rdf-schema#label
Selventa
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http://www.w3.org/ns/prov#hadPrimarySource
http://www.ncbi.nlm.nih.gov/pubmed/10964931
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http://www.w3.org/ns/prov#wasDerivedFrom
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http://purl.org/dc/terms/created
2014-07-03T14:29:31.707+02:00
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http://orcid.org/0000-0001-6818-334X
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http://orcid.org/0000-0002-1267-0234