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All Rights Reserved. http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Small Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/dc/terms/license Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAtincC7EowNCTJP3cMLK9iAHSXryIAJaEDERYTyqZj0o#_7 http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/pav/version 1.6 http://www.tkuhn.ch/bel2nanopub/RAtincC7EowNCTJP3cMLK9iAHSXryIAJaEDERYTyqZj0o#_6 http://www.w3.org/ns/prov#value Here we examine the nature of the physical interaction between the αvβ3 integrin and two receptor tyrosine kinases (RTKs), the platelet-derived growth factor receptor β (PDGF-Rβ) and the vascular endothelial growth factor receptor 2 (VEGF-R2, also known as KDR and flk-1). Both of these RTKs associate with the αvβ3 integrin but do not associate with β1 integrins. Furthermore, growth factor stimulation of these RTKs promotes increased cell proliferation and migration when cells are attached to the αvβ3 ligand, vitronectin. http://www.tkuhn.ch/bel2nanopub/RAtincC7EowNCTJP3cMLK9iAHSXryIAJaEDERYTyqZj0o#_6 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/10964931 http://www.tkuhn.ch/bel2nanopub/RAtincC7EowNCTJP3cMLK9iAHSXryIAJaEDERYTyqZj0o#_7 http://www.w3.org/2000/01/rdf-schema#comment support@belframework.org http://www.tkuhn.ch/bel2nanopub/RAtincC7EowNCTJP3cMLK9iAHSXryIAJaEDERYTyqZj0o#_7 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAtincC7EowNCTJP3cMLK9iAHSXryIAJaEDERYTyqZj0o#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/10964931 http://www.tkuhn.ch/bel2nanopub/RAtincC7EowNCTJP3cMLK9iAHSXryIAJaEDERYTyqZj0o#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAtincC7EowNCTJP3cMLK9iAHSXryIAJaEDERYTyqZj0o#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAtincC7EowNCTJP3cMLK9iAHSXryIAJaEDERYTyqZj0o#_6 http://www.tkuhn.ch/bel2nanopub/RAtincC7EowNCTJP3cMLK9iAHSXryIAJaEDERYTyqZj0o#pubinfo http://www.tkuhn.ch/bel2nanopub/RAtincC7EowNCTJP3cMLK9iAHSXryIAJaEDERYTyqZj0o http://purl.org/dc/terms/created 2014-07-03T14:29:31.707+02:00 http://www.tkuhn.ch/bel2nanopub/RAtincC7EowNCTJP3cMLK9iAHSXryIAJaEDERYTyqZj0o http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAtincC7EowNCTJP3cMLK9iAHSXryIAJaEDERYTyqZj0o http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234