@prefix this: <http://purl.org/np/RAtomgSlbzkMmMrbo1o1POK357alBKXM4SqjeJIFI9O20> .
@prefix sub: <http://purl.org/np/RAtomgSlbzkMmMrbo1o1POK357alBKXM4SqjeJIFI9O20#> .
@prefix drugbank: <http://identifiers.org/drugbank/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix mondo: <http://purl.obolibrary.org/obo/MONDO_> .
@prefix pav: <http://purl.org/pav/> .
@prefix infores: <https://w3id.org/biolink/infores/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix ntemplate: <https://w3id.org/np/o/ntemplate/> .
@prefix orcid: <https://orcid.org/> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix pmid: <http://www.ncbi.nlm.nih.gov/pubmed/> .
@prefix ncit: <http://purl.obolibrary.org/obo/NCIT_> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix biolink: <https://w3id.org/biolink/vocab/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix npx: <http://purl.org/nanopub/x/> .

sub:Head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubInfo;
    a np:Nanopublication .
}

sub:assertion {
  drugbank:DB00656 a biolink:Drug;
    rdfs:label "Trazodone";
    biolink:category biolink:Drug .
  
  mondo:0005090 a biolink:Disease;
    rdfs:label "schizophrenia";
    biolink:category biolink:Disease .
  
  sub:association rdf:object mondo:0005090;
    rdf:predicate biolink:treats;
    rdf:subject drugbank:DB00656;
    a biolink:ChemicalToDiseaseOrPhenotypicFeatureAssociation;
    rdfs:label "While trazodone has only been FDA approved for use in the treatment of major depressive disorder, it has been used off label for numerous conditions including insomnia, anxiety, dementia, Alzheimer's disease, substance abuse, schizophrenia, bulimia, and fibromyalgia.";
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:ChemicalToDiseaseOrPhenotypicFeatureAssociation;
    biolink:has_population_context sub:context;
    biolink:publications pmid:30194544;
    biolink:relation ncit:C94303 .
  
  sub:context a biolink:Cohort;
    rdfs:label "adults";
    biolink:category biolink:Cohort .
}

sub:provenance {
  sub:assertion prov:wasAttributedTo orcid:0000-0002-7641-6446 .
}

sub:pubInfo {
  sub:sig npx:hasAlgorithm "RSA";
    npx:hasPublicKey "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCR9fz0fKCdWOWC+pxhkQhEM/ppbdIYe5TLSdj+lJzSlv9mYBaPgrzVezSwwbmhlHBPDZa4/vHycU315BdmUGq+pXllp9+rWFfrb+kBJwhZjpG6BeyyXBsRFz4jmQVxl/ZYHilQTh/XalYzKkEAyTiEMPee4Kz61PaWOKH24CsnOQIDAQAB";
    npx:hasSignature "GRfvcvyOl9Y2DNFgZWO7hp/HiY0IQP9kJrz9ORdwE+aQhwkDH3J0Y60tQOQAypCrI9VAspi+flzpxdWPFP0kaoBQ7J8cnyS6Ch5YQYHIZ7qqFXVvj1NZsgnTrC36qVZiQr24KZLR5O1bfvIcQmgTf3s4ZF//hoTALaWLVqLbtJ4=";
    npx:hasSignatureTarget this: .
  
  this: prov:generatedAtTime "2022-09-16T11:53:17.626978"^^xsd:dateTime;
    prov:wasAttributedTo orcid:0000-0002-1501-1082;
    ntemplate:wasCreatedFromTemplate <http://purl.org/np/RAhNHZw6Urw_Mccs4qy6Ws3C9CRuaHpQx8AwuApbWkqnY> .
  
  biolink: pav:version "2.3.0" .
}