@prefix this: <http://www.tkuhn.ch/bel2nanopub/RA-0MEkPYDhb298btN_oqdhLVhi_91pNNS205Y8VxEqS4> .
@prefix sub: <http://www.tkuhn.ch/bel2nanopub/RA-0MEkPYDhb298btN_oqdhLVhi_91pNNS205Y8VxEqS4#> .
@prefix beldoc: <http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix dce: <http://purl.org/dc/elements/1.1/> .
@prefix pav: <http://purl.org/pav/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix belv: <http://www.selventa.com/vocabulary/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix Protein: <http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080> .
@prefix hgnc: <http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=> .
@prefix geneProductOf: <http://purl.obolibrary.org/obo/RO_0002204> .
@prefix go: <http://amigo.geneontology.org/amigo/term/GO:> .
@prefix mesh: <http://purl.bioontology.org/ontology/MSH/> .
@prefix occursIn: <http://purl.obolibrary.org/obo/BFO_0000066> .
@prefix hasAnnotation: <http://semanticscience.org/resource/SIO_000255> .
@prefix species: <http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=> .
@prefix pubmed: <http://www.ncbi.nlm.nih.gov/pubmed/> .
@prefix orcid: <http://orcid.org/> .
sub:Head {
  this: np:hasAssertion sub:assertion ;
    np:hasProvenance sub:provenance ;
    np:hasPublicationInfo sub:pubinfo ;
    a np:Nanopublication .
}
sub:assertion {
  sub:_1 geneProductOf: hgnc:11892 ;
    a Protein: .
  sub:_2 occursIn: mesh:D042783 , species:9606 ;
    hasAnnotation: sub:_3 ;
    rdf:object go:0034113 ;
    rdf:predicate belv:increases ;
    rdf:subject sub:_1 ;
    a rdf:Statement .
  sub:_3 dct:subject "TextLocation" ;
    rdf:value "Abstract" .
  sub:assertion rdfs:label "p(HGNC:TNF) -> bp(GO:\"heterotypic cell-cell adhesion\")" .
}
sub:provenance {
  beldoc: dce:description "Approximately 2000 hand curated statements drawn from 57 PubMeds." ;
    dce:rights "Copyright (c) 2011-2012, Selventa. All Rights Reserved." ;
    dce:title "BEL Framework Small Corpus Document" ;
    dct:license "Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License" ;
    pav:authoredBy sub:_5 ;
    pav:version "1.6" .
  sub:_4 prov:value """Adhesion of HT-29 cells on a monolayer of HUVEC pretreated with TNFα was dependent
on E-selectin expression but was independent of SAPK2/p38 activity of both HUVEC
and tumor cells. The adhesion of HT-29 cells to E-selectin-expressing HUVEC led
to the activation of SAPK2/p38 in the tumor cells as reflected by the increased
phosphorylation of the actin-polymerizing factor HSP27 by mitogen-activated protein
kinase 2/3, a direct target of SAPK2/p38. Moreover, a recombinant E-selectin/Fc
chimera quickly increased the activation of SAPK2/p38 in HT-29 cells. Blocking
the increased activity of SAPK2/p38 of HT-29 cells by SB203580 or by expressing
a dominant negative form of SAPK2/p38 inhibited their transendothelial migration.""" ;
    prov:wasQuotedFrom pubmed:11448946 .
  sub:_5 rdfs:comment "support@belframework.org" ;
    rdfs:label "Selventa" .
  sub:assertion prov:hadPrimarySource pubmed:11448946 ;
    prov:wasDerivedFrom beldoc: , sub:_4 .
}
sub:pubinfo {
  this: dct:created "2014-07-03T14:29:33.293+02:00"^^xsd:dateTime ;
    pav:createdBy orcid:0000-0001-6818-334X , orcid:0000-0002-1267-0234 .
}