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All Rights Reserved. http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Small Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/dc/terms/license Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RA1wgoUgbhNqoxJdJpapq4vDqBV8pWffhDDeC4F2ZPl7E#_7 http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/pav/version 1.6 http://www.tkuhn.ch/bel2nanopub/RA1wgoUgbhNqoxJdJpapq4vDqBV8pWffhDDeC4F2ZPl7E#_6 http://www.w3.org/ns/prov#value In ECs, VEGF stimulates ARF6 association with Rac1, which is cotemporaneous with Rac1 activation. The dominant negative ARF6 (T27N),inhibits VEGF-stimulated GTP-loading of Rac1, ROS production, and VEGFR2 autophosphorylation. 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