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Results
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p(RGD:Igf1) -> kin(p(PFR:"MAPK Erk1/3 Family"))
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Approximately 2000 hand curated statements drawn from 57 PubMeds.
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Copyright (c) 2011-2012, Selventa. All Rights Reserved.
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BEL Framework Small Corpus Document
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Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License
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Intracellular signaling. Infusion of IGF-I resulted in an approximate fivefold increase
in the phosphorylation of ERKs 1 and 2 (Fig. 4), whereas the total ERK levels
were unchanged vs. contralateral muscles (data not shown). Coinfusion (IGF+PD)
completely blunted the increase in ERK1 phosphorylation and significantly reduced
the increase in ERK2 phosphorylation (Fig. 4B). Similar to ERK2, the phosphorylation
of S6K1 was increased fivefold in the IGF and 2.8-fold in the IGF+PD
muscles (Fig. 5). The infusion protocols did not impact the total amount of S6K1
(data not shown).
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support@belframework.org
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Selventa
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2014-07-03T14:29:34.210+02:00
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