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All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RA5PWgtJc69erSWSpGHvnZTVHJ4AFxO15b3Yxqhm_Lah8#_5 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RA5PWgtJc69erSWSpGHvnZTVHJ4AFxO15b3Yxqhm_Lah8#_3 http://purl.org/dc/elements/1.1/identifier Entrez Gene summary Human CIDEA http://www.tkuhn.ch/bel2nanopub/RA5PWgtJc69erSWSpGHvnZTVHJ4AFxO15b3Yxqhm_Lah8#_3 http://purl.org/dc/elements/1.1/title Entrez Gene summary Human CIDEA http://www.tkuhn.ch/bel2nanopub/RA5PWgtJc69erSWSpGHvnZTVHJ4AFxO15b3Yxqhm_Lah8#_3 http://purl.org/dc/elements/1.1/type Online Resource http://www.tkuhn.ch/bel2nanopub/RA5PWgtJc69erSWSpGHvnZTVHJ4AFxO15b3Yxqhm_Lah8#_4 http://www.w3.org/ns/prov#value % Entrez Gene summary: Human: This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. 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