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http://www.tkuhn.ch/bel2nanopub/RA5PWgtJc69erSWSpGHvnZTVHJ4AFxO15b3Yxqhm_Lah8#_1
http://purl.obolibrary.org/obo/RO_0002204
http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=1976
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p(HGNC:CIDEA) -> path(SDIS:"Type II diabetes")
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Approximately 61,000 statements.
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Copyright (c) 2011-2012, Selventa. All rights reserved.
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BEL Framework Large Corpus Document
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1.4
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Entrez Gene summary Human CIDEA
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Entrez Gene summary Human CIDEA
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Online Resource
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% Entrez Gene summary: Human: This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Two alternative transcripts encoding different isoforms have been identified.
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Selventa
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2014-07-03T14:29:43.645+02:00
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