@prefix dc: . @prefix this: . @prefix sub: . @prefix beldoc: . @prefix rdfs: . @prefix rdf: . @prefix xsd: . @prefix dce: . @prefix pav: . @prefix np: . @prefix belv: . @prefix prov: . @prefix go: . @prefix Protein: . @prefix hgnc: . @prefix geneProductOf: . @prefix hasAgent: . @prefix hasAnnotation: . @prefix species: . @prefix occursIn: . @prefix mesh: . @prefix pubmed: . @prefix orcid: . sub:Head { this: np:hasAssertion sub:assertion; np:hasProvenance sub:provenance; np:hasPublicationInfo sub:pubinfo; a np:Nanopublication . } sub:assertion { sub:_1 hasAgent: sub:_2; a go:0005525 . sub:_2 geneProductOf: hgnc:6407; a Protein: . sub:_3 hasAgent: sub:_4; a go:0016301 . sub:_4 geneProductOf: hgnc:9829; a Protein: . sub:_5 occursIn: mesh:D003593, species:9606; hasAnnotation: sub:_6; rdf:object sub:_3; rdf:predicate belv:directlyIncreases; rdf:subject sub:_1; a rdf:Statement . sub:_6 dc:subject "TextLocation"; rdf:value "Review" . sub:assertion rdfs:label "gtp(p(HGNC:KRAS)) => kin(p(HGNC:RAF1))" . } sub:provenance { beldoc: dce:description "Approximately 2000 hand curated statements drawn from 57 PubMeds."; dce:rights "Copyright (c) 2011-2012, Selventa. All Rights Reserved."; dce:title "BEL Framework Small Corpus Document"; dc:license "Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License"; pav:authoredBy sub:_8; pav:version "1.6" . sub:_7 prov:value """The effector domain of GTP-bound Ras binds to C-Raf through the RBD and CRD in the CR1. Although binding to both sites is required for Raf activation, the most critical interaction is between Ras-GTP and the RBD.127 All Ras isoforms are capable of interacting with Raf, but K-Ras is the most potent activator, whereas N-Ras is much more efficient than H-Ras.128 The interaction between Ras and C-Raf alone is insufficient to activate C-Raf, but it serves to translocate C-Raf to the cell membrane where it can be activated."""; prov:wasQuotedFrom pubmed:16170185 . sub:_8 rdfs:comment "support@belframework.org"; rdfs:label "Selventa" . sub:assertion prov:hadPrimarySource pubmed:16170185; prov:wasDerivedFrom beldoc:, sub:_7 . } sub:pubinfo { this: dc:created "2014-07-03T14:29:30.481+02:00"^^xsd:dateTime; pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 . }