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a(CHEBI:"nitric oxide") -| bp(GOBP:"apoptotic process")
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Approximately 2000 hand curated statements drawn from 57 PubMeds.
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Copyright (c) 2011-2012, Selventa. All Rights Reserved.
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BEL Framework Small Corpus Document
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Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License
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Shear stress enhances expression of the gene encoding the endothelial nitric oxide
synthase (eNOS) and further stimulates its enzymatic activity, leading to physiologic
low concentrations of nitric oxide (NO) within endothelial cells [44–46].
This continuous generation of NO prevents the apoptosis of endothelial cells,
thereby protecting the endothelial monolayer from injury [47,48].
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2014-07-03T14:31:14.909+02:00
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