. . . . . . . . . . . . . . . . . . . "TextLocation" . "Review" . "gtp(p(HGNC:NRAS)) => kin(p(HGNC:RAF1))" . "Approximately 2000 hand curated statements drawn from 57 PubMeds." . "Copyright (c) 2011-2012, Selventa. All Rights Reserved." . "BEL Framework Small Corpus Document" . "Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License" . . "1.6" . "The effector domain of GTP-bound Ras binds to C-Raf through the RBD and CRD in the\nCR1. Although binding to both sites is required for Raf activation, the most critical\ninteraction is between Ras-GTP and the RBD.127 All Ras isoforms are capable\nof interacting with Raf, but K-Ras is the most potent activator, whereas N-Ras\nis much more efficient than H-Ras.128 The interaction between Ras and C-Raf\nalone is insufficient to activate C-Raf, but it serves to translocate C-Raf to\nthe cell membrane where it can be activated." . . "support@belframework.org" . "Selventa" . . . . "2014-07-03T14:29:30.478+02:00"^^ . . .