. . . . . . . . . . . . . . . . . "TextLocation" . "Review" . "phos(complex(SCOMP:\"PP2A Complex\")) =| p(HGNC:RAF1,pmod(P,S))" . "Approximately 2000 hand curated statements drawn from 57 PubMeds." . "Copyright (c) 2011-2012, Selventa. All Rights Reserved." . "BEL Framework Small Corpus Document" . "Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License" . . "20131211" . "C-Raf exists in the cytoplasm as a 300- to 500-kd protein complex. The complex consists\nof C-Raf, heat shock protein 90 (Hsp90), and the dimeric protein cofactor\n14-3-3. 14-3-3 binds to two specific phosphoserine residues of C-Raf, which masks\nits kinase domain and inactivates the protein. The binding of Ras to C-Raf displaces\nthe 14-3-3 dimer, rendering C-Raf accessible to dephosphorylation by protein\nphosphatase 2A.126" . . "support@belframework.org" . "Selventa" . . . . "2014-07-03T14:31:15.617+02:00"^^ . . .