Activation of anterior HOX genes in hindbrain development during early embryogenesis

TNFs bind their physiological receptors

Signaling by FGFR3

RHO GTPases Activate NADPH Oxidases

XBP1(S) activates chaperone genes

TP53 Regulates Transcription of Cell Death Genes

Uptake and function of diphtheria toxin

C-type lectin receptors (CLRs)

BMAL1:CLOCK,NPAS2 activates circadian gene expression

Cellular response to heat stress

Macroautophagy

Lysosomal oligosaccharide catabolism

SUMOylation of DNA damage response and repair proteins

SIDS Susceptibility Pathways

Selenoamino acid metabolism

DNA IR-Double Strand Breaks (DSBs) and cellular response via ATM

RNA polymerase II transcribes snRNA genes

VEGFA-VEGFR2 Signaling Pathway

Signaling by FGFR2

Signaling by Leptin

Retinoid metabolism and transport

Hedgehog 'off' state

rRNA modification in the nucleus and cytosol

DNA Double Strand Break Response

Regulation of TP53 Expression and Degradation

Sialic acid metabolism

Class I MHC mediated antigen processing & presentation

Senescence-Associated Secretory Phenotype (SASP)

RHO GTPases activate PKNs

NIK-->noncanonical NF-kB signaling

Intra-Golgi and retrograde Golgi-to-ER traffic

Signaling by FGFR1

Surfactant metabolism

Base-Excision Repair, AP Site Formation

POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation

Amyloid fiber formation

TP53 Regulates Metabolic Genes

Hedgehog 'on' state

Serotonin Receptor 2 and ELK-SRF/GATA4 signaling

Histidine, lysine, phenylalanine, tyrosine, proline and tryptophan catabolism

Mismatch Repair

Vitamin D (calciferol) metabolism

Metallothioneins bind metals

RHO GTPases Activate WASPs and WAVEs

MAPK6/MAPK4 signaling

TCF dependent signaling in response to WNT

Nonhomologous End-Joining (NHEJ)

Amine-derived hormones

EPH-Ephrin signaling

HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)

DNA Damage/Telomere Stress Induced Senescence

RHO GTPases activate CIT

Branched-chain amino acid catabolism

Uptake and function of anthrax toxins

Resolution of Abasic Sites (AP sites)

ROS, RNS production in phagocytes

Regulation of TP53 Activity through Association with Co-factors

trans-Golgi Network Vesicle Budding

Hedgehog ligand biogenesis

TNF signaling

Fanconi Anemia Pathway

TRAIL signaling

TP53 Regulates Transcription of Cell Cycle Genes

Major pathway of rRNA processing in the nucleolus and cytosol

SUMOylation of chromatin organization proteins

Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3

Regulated Necrosis

TNFR2 non-canonical NF-kB pathway

Mitochondrial biogenesis

Beta-catenin independent WNT signaling

Interleukin-20 family signaling

Signaling by PTK6

Vitamin E

Class A/1 (Rhodopsin-like receptors)

Nucleobase catabolism

Phase II - Conjugation of compounds

Biosynthesis of DHA-derived SPMs

Chromatin organization

ESR-mediated signaling

Biosynthesis of DPA-derived SPMs

G alpha (12/13) signalling events

Activation of NMDA receptors and postsynaptic events

E3 ubiquitin ligases ubiquitinate target proteins

Transcriptional regulation by RUNX1

Intestinal infectious diseases

Interleukin-12 family signaling

Transcriptional Regulation by E2F6

Other interleukin signaling

Deubiquitination

Intestinal absorption

Plasma lipoprotein assembly, remodeling, and clearance

Pentose phosphate pathway

Regulation of RUNX1 Expression and Activity

Transcriptional regulation by RUNX2

Integrin alphaIIb beta3 signaling

RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function

DNA IR-damage and cellular response via ATR

Transcriptional regulation by RUNX3

Interleukin-15 signaling

Triglyceride metabolism

Interleukin-9 signaling

Regulation of TLR by endogenous ligand

Neurexins and neuroligins

Collagen chain trimerization

G alpha (i) signalling events

rRNA modification in the mitochondrion

Cilium Assembly

Ebola Virus Pathway on Host

Phase I - Functionalization of compounds

OAS antiviral response

RAB GEFs exchange GTP for GDP on RABs

Fatty acyl-CoA biosynthesis

Biosynthesis of EPA-derived SPMs

Mitochondrial Fatty Acid Beta-Oxidation

Interleukin-4 and Interleukin-13 signaling

Digestion

RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)

DNA Replication Pre-Initiation

Import of palmitoyl-CoA into the mitochondrial matrix

RET signaling

Nicotinate metabolism

Biosynthesis of electrophilic ?-3 PUFA oxo-derivatives

Galactose catabolism

Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation

PTEN Regulation

Signaling by MET

Nucleotide salvage

Interleukin-10 signaling

SUMOylation of transcription cofactors

Neddylation

Antimicrobial peptides

p75 NTR receptor-mediated signalling

Peroxisomal protein import

Cargo recognition for clathrin-mediated endocytosis

Serine biosynthesis

COPII-mediated vesicle transport

Glycogen metabolism

Listeria monocytogenes entry into host cells

Transcription from mitochondrial promoters

Lipid particle organization

Interconversion of nucleotide di- and triphosphates

Activation of kainate receptors upon glutamate binding

Transcriptional Regulation by MECP2

TBC/RABGAPs

RNA Polymerase I Transcription

Ketone body metabolism

Class B/2 (Secretin family receptors)

Glucose metabolism

COPI-mediated anterograde transport

Keratinization

Protein ubiquitination

Ion channel transport

Signaling by Erythropoietin

Synaptic adhesion-like molecules

Nucleobase biosynthesis

Glutamate binding, activation of AMPA receptors and synaptic plasticity

Signaling by Retinoic Acid

Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors

Clathrin-mediated endocytosis

RAB geranylgeranylation

Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation

Signaling by NTRK3 (TRKC)

Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models

Reelin signalling pathway

Neutrophil degranulation

SUMOylation of intracellular receptors

Interleukin-6 family signaling

G alpha (q) signalling events

Regulation of RUNX2 expression and activity

Butyrophilin (BTN) family interactions

Formation of xylulose-5-phosphate

Regulation of mitotic cell cycle

Protein methylation

Class C/3 (Metabotropic glutamate/pheromone receptors)

Pyrophosphate hydrolysis

G alpha (s) signalling events

RNA Polymerase III Transcription

PI3K Cascade

GABA receptor activation

Mitochondrial calcium ion transport

Aryl hydrocarbon receptor signalling

Receptor-type tyrosine-protein phosphatases

Fructose metabolism

Synthesis of Lipoxins (LX)

Acetylcholine binding and downstream events

HSP90 chaperone cycle for steroid hormone receptors (SHR)

NADPH regeneration

SUMOylation of ubiquitinylation proteins

Choline catabolism

Intracellular oxygen transport

G alpha (z) signalling events
Signaling by NTRK2 (TRKB)
SUMOylation of SUMOylation proteins
Cellular hexose transport
Serotonin Receptor 4/6/7 and NR3C Signaling
Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways
Metabolism of nitric oxide
Signaling by VEGF
Opioid Signalling
Folate Metabolism
Selenium Micronutrient Network
Folic Acid Network
Regulation of DNA replication
Eukaryotic Translation Elongation
Cell surface interactions at the vascular wall
Complement cascade
Formation of Fibrin Clot (Clotting Cascade)
Response to elevated platelet cytosolic Ca2+
Methylation
Vitamin B12 Metabolism
Folate-Alcohol and Cancer Pathway Hypotheses
One carbon metabolism and related pathways
Interleukin-1 family signaling
DDX58/IFIH1-mediated induction of interferon-alpha/beta
TCR signaling
Integration of energy metabolism
Nucleotide Excision Repair
Processing of Capped Intron-Containing Pre-mRNA
Cell Cycle Checkpoints
Transport of vitamins, nucleosides, and related molecules
DNA Damage Bypass
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA
Metabolism of water-soluble vitamins and cofactors
Apoptotic execution phase
Mitotic G2-G2/M phases
miRNAs involved in DNA damage response
Fluoropyrimidine Activity
TP53 Network
Apoptosis Modulation and Signaling
TCA Cycle
Valine, leucine and isoleucine degradation
Netrin-1 signaling
Regulation of toll-like receptor signaling pathway
Serotonin Transporter Activity
Signaling by ROBO receptors
Telomere Maintenance
Neurotransmitter release cycle
Mitotic G1-G1/S phases
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
The effect of Glucocorticoids on target gene expression
Cell junction organization
Fatty Acid Beta Oxidation
Nucleosome assembly
Arachidonate Epoxygenase / Epoxide Hydrolase
Eicosanoid Synthesis
Arachidonate Epoxygenase Epoxide Hydrolase
Vitamin D Metabolism
Unfolded Protein Response (UPR)
Processing of Capped Intronless Pre-mRNA
RNA Polymerase II Transcription
Transport of inorganic cations/anions and amino acids/oligopeptides
Intrinsic Pathway for Apoptosis
Protein folding
ABC-family proteins mediated transport
Regulation of Apoptosis
Synthesis of DNA
L1CAM interactions
Iron Homeostasis
Peroxisomal lipid metabolism
Signaling by EGFR
One Carbon Metabolism